Periorbital papules as a presenting sign in multiple myeloma with AL amyloidosis.
نویسندگان
چکیده
Monash Haematology, Monash Health, Clayton, Victoria, Australia Monash University School of Clinical Sciences at Monash Health, Clayton, Victoria, Australia Centre for Cancer Research, Hudson Institute of Medical Research Clayton, Victoria, Australia Immunology/Molecular Immunology Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia Department of Medical Biology, The University of Melbourne, Parkville, Victoria Australia Alfred Pathology Service and Department of Clinical Haematology, Alfred Health, Commercial Road, Melbourne Victoria Australia
منابع مشابه
A case of primary systemic amyloidosis with nail dystrophy
We hereby report a 79-year-old Iranian man presenting with nail dystrophy and subsequent development of purpuric and ecchymotic plaques, hemorrhagic bullae, and infiltrated papules on the head, neck and trunk. Histological examination of the gingiva, bone marrow aspiration, and biopsy confirmed the diagnosis of primary systemic amyloidosis. In this case, nail dystrophy was the presenting sign o...
متن کاملMultiple myeloma-associated light chain amyloidosis presenting as verrucous lingual masses.
Sir, Multiple myeloma is a monoclonal B-cell neoplasm, which is characterized by autonomous proliferation of immunoglobulin-secreting plasma cells, capable of synthesizing amyloidogenic light chains (AL). AL amyloidosis is characterized by extracellular deposition of eosinophilic, homogeneous, amorphous material composed of fibrillary protein, containing light chain fragments (1). The oral clin...
متن کاملA Rare Presentation of Multiple Myeloma: A Case Report of Hepatic Amyloidosis
The clinically reported case of liver involvement with multiple myeloma (MM) is rare. Amyloidosis, defined as a tissue deposition of clonal light-chain fibrils, has been reported in 10-15% of the MM patients. We described a rare MM patient with the primal presentation of fulminant hepatic failure and biliary system involvement due to amyloidosis. Our patient had the primal symptoms of hyperbili...
متن کاملParaneoplastic neurological syndromes
Necrobiotic xanthogranuloma This presents as multiple sharply demarcated, indurated, non-tender dermal or subcutaneous nodules and plaques. Periorbital involvement is common. Lesions vary from violaceous to red orange, and enlarge to form infiltrative plaques that may show central atrophy. Though most of the lesions are asymptomatic, some may be pruritic or painful. Ulceration and scarring are ...
متن کاملCASE REPORT Amyloidosis in bilateral external auditory canals
To cite: Hosoi T, Dhaliwal G, Tokuda Y. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013200753 SUMMARY We report a 76-year-old man, a retired farmer, presenting with bilateral external auditory canal obstruction. Skin examination revealed multiple pruritic nodules and periorbital purpura. Ear canal opening surgery was performed. Skin and ear canal biopsy revea...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- BMJ case reports
دوره 2017 شماره
صفحات -
تاریخ انتشار 2017